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PTCB PTCE Exam Questions
Page 7 of 50
121.
Which statement is false in regard to storage of hazardous drugs (HD)?
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Storage of HD should be nearby the employee break areas, away from patients and visitors.
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Access to areas where HDs are handled must be restricted to authorized personnel.
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Storage of HDs should be to prevent spillage and breakage.
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Storage must meet appropriate safety precautions.
Correct answer: Storage of HD should be by the employee break areas, away from patients and visitors.
Good practices regarding storage of HD include the following:
- Storage of HDs should be located away from the employee break areas, not nearby. It should also be located away from patients and visitors.
- Access to areas where HDs are handled must be restricted to authorized personnel.
- Storage of HDs should be to prevent spillage and breakage.
- Storage must meet appropriate safety precautions.
122.
Which of the following vitamins is found in sunlight?
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Vitamin D3
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Vitamin D2
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Vitamin A
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Vitamin E
Correct answer: Vitamin D3
Vitamin D3 (cholecalciferol) is a fat-soluble vitamin used to treat and prevent bone loss. The natural source can be found in sunlight but it is also sold as capsules over the counter (OTC).
Vitamin A (retinol) prevents an eye condition called keratomalacia. Vitamin A can be found in milk, butter, cheese, liver, and fish oils.
Vitamin D2 (ergocalciferol) is a vitamin used to prevent rickets in small children and osteomalacia in adults. It is found in fortified foods such as butter, milk, cheese, and egg yolk, as well as in fish oils. These are also found OTC as capsules.
Vitamin E (tocopherols) is an antioxidant for unsaturated fatty acids. This vitamin can be found in soybean oil, wheat and rice germ, nuts, eggs, and leafy green vegetables.
123.
All except which of the following pieces of information is required on a prescription label?
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Beyond-use date
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Name of the drug manufacturer
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Prescription number
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Name and address of pharmacy
Correct answer: Beyond-use date
The beyond-use date is a piece of information required on repacked medications, but it is not necessary on a prescription label.
The following information is required on a prescription label:
- Fill date
- Prescription number
- Pharmacy’s name, address, and telephone number
- Patient’s name
- Prescriber’s name
- Directions for use
- Brand or generic name
- Medication strength
- Drug manufacturer
- Quantity
124.
Who is required to retain the brown copy (first page) of DEA Form 222?
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Supplier
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DEA
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Pharmacy
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Patient
Correct answer: Supplier
The supplier is required to retain the brown copy (first page) of DEA Form 222.
The DEA is required to retain the green copy (second page) of DEA Form 222. The pharmacy is required to retain the blue copy (third page) of DEA Form 222. The patient does not receive a copy of DEA Form 222.
125.
Which of the following is an example of an antianxiety agent?
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Clonazepam (Klonopin)
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Afrin (oxymetazoline)
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Patanol (olopatadine)
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Flagyl (metronidazole)
Correct answer: Clonazepam (Klonopin)
Klonopin is the brand name for clonazepam and is classified as an antianxiety agent. Other antianxiety agents include Xanax, BuSpar, Librium, Tranxene, Valium, and Ativan.
Afrin is the brand name for oxymetazoline and is classified as a decongestant. Patanol is the brand name for olopatadine and is classified as an antihistamine. Flagyl is the brand name for metronidazole and is classified as an antiprotozoal agent.
126.
Which HEPA filtering system is responsible for the containment of hazardous materials?
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Class III
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Class I
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Class II
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Class IV
Correct answer: Class III
Class III HEPA filtering systems are responsible for the containment of hazardous materials. The risk levels associated with Class III are high-risk biologicals, and Class III has a biosafety level III.
Class I HEPA filtering systems filter air before it is exhausted. Class II HEPA filtering systems filter exhaust air to a room or to a facility exhaust system. Class IV is incorrect because there are only three classes of HEPA filtering systems.
127.
Simvastatin is an HMG-CoA reductase inhibitor used to reduce cholesterol. When is it best for a patient to take simvastatin?
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At night
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In the morning
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Before meals
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After meals
Correct answer: At night
It is best for patients to take statins at night. Statins are taken to help reduce cholesterol, and because most of the body’s cholesterol is produced at night, statins are more effective when taken at night. The HMG-CoA reductase inhibitor (statin) drug class is categorized as a pregnancy category X.
It is not best for patients to take statins in the morning, before meals, or after meals.
128.
Which organization is responsible for auditing the destruction of controlled substances?
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Drug Enforcement Agency (DEA)
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Food and Drug Administration (FDA)
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State boards of pharmacy
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United States Pharmacopeia (USP)
Correct answer: Drug Enforcement Agency (DEA)
The DEA is responsible for auditing the destruction of controlled substances. The DEA must be notified two weeks prior to the destruction of controlled substances, and DEA Form 41 must be completed and maintained by the pharmacy for two years.
The FDA is responsible for ensuring that medications are safe. The state boards of pharmacy are responsible for overseeing pharmacy practices. The USP is responsible for setting pharmacy standards.
129.
ISO Class 5 must not exceed which of the following number of particles?
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Not more than 3520 particles
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Not more than 352 particles
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Not more than 352,000 particles
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Not more than 3,520,000 particles
Correct answer: Not more than 3520 particles
Total particle counts must be performed no less than every 6 months and must not exceed the following requirement per cubic meter of air:
- ISO Class 4: Not more than 352 particles
- ISO Class 5: Not more than 3520 particles
- ISO Class 7: Not more than 352,000 particles
- ISO Class 8: Not more than 3,520,000 particles
130.
Which HEPA filtering system filters exhaust air to a room or to a facility exhaust system?
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Class II
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Class I
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Class III
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Class IV
Correct answer: Class II
Class II HEPA filtering systems filter exhaust air to a room or to a facility exhaust system. The risk levels associated with Class II are low-risk to moderate-risk biologicals, and Class II has a biosafety level II.
Class I HEPA filtering systems filter air before it is exhausted. Class III HEPA filtering systems are responsible for the containment of hazardous materials. Class IV is incorrect because there are only three classes of HEPA filtering systems.
131.
How does the Combat Methamphetamine Epidemic Act of 2005 (CMEA) require pseudoephedrine products to be packaged and sold?
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In blister packs
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In child-proof vials
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In amber vials
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In packages of 12
Correct answer: In blister packs
The Combat Methamphetamine Epidemic Act of 2005 (CMEA) requires pseudoephedrine products to be packaged and sold in blister packs. CMEA requires pharmacies to secure pseudoephedrine products from consumers.
CMEA does not allow pseudoephedrine products to be sold as loose tablets or capsules, which eliminates them from being packaged in child-proof vials or amber vials. CMEA does not state that pseudoephedrine products need to be sold in packages of 12.
132.
Master Formulation Record (MFR) contains all except which of the following?
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AWP
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Calculations
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Stability data
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List of ingredients
Correct answer: AWP
MFR provides all the following details except for AWP (average wholesale price):
- List of ingredients and quantities
- Calculations
- Needed equipment
- Instructions for mixing
- Stability data
- Labeling information
- Requirement for packaging and storage
- Quality control procedures
133.
If you have 20 grams of a substance, how many micrograms do you have?
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20,000,000 μg
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200,000 μg
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20,000 μg
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2,000 μg
Correct answer: 20,000,000 μg
To convert grams to micrograms, know that 1 gram = 1,000 milligrams and 1 milligram = 1,000 micrograms.
Therefore, 20 g × 1,000 mg/1 g = 20,000 mg and 20,000 mg × 1,000 μg/1 mg = 20,000,000 μg.
134.
Which of the following classes of drugs may decrease the effectiveness of oral contraceptives?
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Antibiotics
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Beta blockers
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Antacids
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Opioids
Correct answer: Antibiotics
Antibiotics may decrease the effectiveness of oral contraceptives. Other drug classes that interact with oral contraceptives include anticonvulsants, antifungals, benzodiazepines, bronchodilators, corticosteroids, lipid-lowering agents, and tricyclic antidepressants.
Beta blockers, antacids, and opioids are not known to decrease the effectiveness of oral contraceptives.
135.
How many days will 240 tablets of hydrocodone last if the prescription’s instructions are to take two tablets every four hours as needed for pain?
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20 days
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30 days
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15 days
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25 days
Correct answer: 20 days
To determine the number of tablets per day, do the following calculation: 2 tablets x 6 times a day (24 hours/4 hours = 6 hours) = 12 tablets per day.
Then, cross multiply to solve: 240 tablets/1 x day/12 tablets = 20 days.
136.
Which piece of community pharmacy automation uses bar codes to read prescription labels to pull and dispense the appropriate drug from its cassettes?
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Baker Cell
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Robot-Rx
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MedCarousel
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Kirby Lester
Correct answer: Baker Cell
Baker Cell is a piece of community pharmacy automation that uses bar codes to read prescription labels to pull and dispense the appropriate drug from its cassettes.
Robot-Rx is a piece of hospital pharmacy automation that reads a patient’s medication record using a bar code reader, pulls the appropriate medication using a bar code reader, and packages the medication to be delivered to the appropriate floor. MedCarousel is a piece of hospital pharmacy automation that uses rotating shelves, pick-to-light technology, and bar code scanning to dispense medications and control inventory. Kirby Lester is a piece of community pharmacy automation that uses a touch screen and a scanning system to count and verify every medication order.
137.
Which of the following is a characteristic of emulsion?
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One liquid is dispersed in another liquid
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Solid particles are dispersed in a liquid vehicle
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Medicated or non-medicated preparations that adhere to the skin by a backing material
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Medication in the form of mist
Correct answer: One liquid is dispersed in another liquid
Emulsion is defined as when one liquid is dispersed in another liquid. For example, water in oil or oil in water.
A suspension is a two-phase system in which solid particles are dispersed in a liquid vehicle.
Plasters are medicated or non-medicated preparations that adhere to the skin by a backing material.
A nebulizer is a device that is used to administer medication in the form of mist.
138.
Which of the following medication does not require completion of DEA Form 106 in the event of theft or significant loss?
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Benzonatate
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Nalorphine
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Carisoprodol
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Modafinil
Correct answer: Benzonatate
All controlled substances from C-II to C-V require completion and submission of DEA Form 106 to the area DEA field office in the event of theft or significant loss.
Benzonatate is not a controlled substance; it is a legend drug that is indicated for cough.
Nalorphine is a C-III, and modafinil and carisoprodol are C-IV controlled substances. Therefore, they all require completion and submission of DEA Form 106 in the event of theft or significant loss.
139.
Which of the following inventory maintenance can result in medication errors?
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Not using the "basket" system to separate patient orders
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Not storing nondrug supplies, such as alcohol, near diluents
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Storing different types of insulin in separate bins in the refrigerator
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Always labeling all stock
Correct answer: Not using the "basket" system to separate patient orders
Medication errors can occur as a result of the processes used involving the pharmacy's inventory. Not using a "basket" system to separate patient orders may result in medication errors.
The following are a few good practices to reduce medication errors:
- Not storing nondrug supplies, such as alcohol, near diluents and products that require reconstitution
- Storing different types of insulin in separate bins in the refrigerator
- Always labeling all stock, including return-to-stock vials, with drug name, strength, expiration date, and NDC number or bar code if possible
140.
All of the following are considered benzodiazepines, except:
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Pristiq
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Xanax
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Valium
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Ativan
Correct answer: Pristiq
Pristiq (desvenlafaxine) is a serotonin-norepinephrine reuptake inhibitor (SNRI).
Xanax (alprazolam), Valium (diazepam) and Ativan (lorazepam) are all benzodiazepines.